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Results The recurrence rate after adjuvant chemotherapy was significantly higher in the GSH group ( n = 28, 31.8%) than that in the Non-GSH group ( n = 39, 22.2%

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There are excellent reviews and clinical guidelines addressing the management of APL.69 In Brazil, the last published recommendations on APL management date from 2013, when the association of ATRA and ATO was not a current practice.10 Therefore, the creation of a Brazilian consensus is particularly needed because: 1) APL is a peculiar subtype of AML that requires specific treatment

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IV infusion therapy can be an effective component of this approach by delivering antioxidants and nutrients that support detoxification and reduce oxidative stress

The results indicated an absence of discernible pathological differences in the histological morphology of all examined organs when compared to the PBS control group ( Figure S27a )