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[ 194 ] The expression of peroxisome proliferatoractivated receptor (PPAR) and PPARdependent adipocyte differentiation is suppressed by BACH1 in primary mouse embryonic fibroblasts, suggesting that BACH1 is an inhibitory regulator of adipocyte differentiation and adipogenesis

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In fact, those with the highest ergothioneine levels had a 44% lower rate of all-cause dementia, 39% lower rate of Alzheimer dementia, and 57% lower rate of nonAlzheimer disease-related dementia than those with the lowest levels

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Similarly, in cerebral ischemia, cannabinoids like dexanabinol protect against neuronal death by reducing NO levels, highlighting nNOS as a potential therapeutic target (Durmaz et al