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SGJ-treated cells were harvested by centrifugation (10,000 g for 5 min at 4C), resuspended in equal volume of simulated pancreatic juice (0.15 g/100 ml bile salt, 1 g/L trypsin, pH 8.0), and incubated at 37C for 3 h at 200 rpm

In addition, the combination of natural compounds with nanosystems faces limitations such as low drug-loading capacity and unstable release profiles, highlighting the urgent need for the development of intelligent nanocarriers to improve delivery precision

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Brief summary This section broadens the concept of metabolicepigenetic integration beyond catalytic reactions, demonstrating that oxidoreductases also act as structural sensors of the cellular redox state

Serum insulin and glucagon-like peptide-1 (GLP-1) levels were measured during oral glucose tolerance test

10.1016/j.semcdb.2017.05.023 Semin