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"Kenyan school children have multiple micronutrient deficiencies, but increased plasma vitamin B-12 is the only detectable micronutrient response to meat or milk supplementation"

This article examines the mechanisms of B12 uptake, practical guidance on supplement timing, and the clinical factors that affect how quickly deficiency can be corrected

Clinical studies have tested doses up to 1000 mg or even 2000 mg daily of NR and found them to be well-tolerated with no serious adverse effects

The dose that reaches fibroblasts is still low compared to what systemic delivery achieves

Vitamin B12 deficiency after total gastrectomy is often thought of as macrocytic anemia, but neurological symptoms can also occur, although they are rare [10,11]

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