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Related studies have demonstrated that Nrf2 is a novel substrate for pERK and pERK can directly phosphorylate Nrf2, promoting activity and nuclear accumulation of Nrf2 [68]

These agents can scavenge free radicals and prevent further damage (Jamshidi et al., 2018)

Am J Respir Cell Mol Biol 39(6):697705 Kinnula VL, Fattman CL, Tan RJ, Oury TD (2005) Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy

Similarly, the GSSG concentration in the digesta of SI1 was significantly higher in the HGSH group than the LGSH group on d5 ( p = 0.029) and d14 ( p = 0.011)