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Rett syndrome (RS) is caused by mutations in the gene methyl-CpG-binding protein 2 (MECP2) Rett syndrome RS is characterized by language and communication problems, learning and coordination difficulties, and they display autistic-like behaviors [362, 363]

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10.1016/j.jacc.2019.11.060 18

PMID 18065594

Although diets rich in choline, L-carnitine, -butyrobetaine, trimethyllysine and betaine are the main sources of TMAO, total intake is also critical for TMAO concentration

Martin D, Rojo AI, Salinas M, Diaz R, Gallardo G, Alam J, De Galarreta CM, Cuadrado A (2004) Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol