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Tumor-derived lactate also impairs the interaction between PD-L1 and anti-PD-L1 antibodies, contributing to ICB resistance, however, combining the monocarboxylate transporter 1 (MCT1) inhibitor AZD3965 with anti-PD-L1 antibodies effectively reduces lactate efflux and treats tumors refractory to PD-1/PD-L1 blockade (380)

Anti-inflammatory steroids are very different in action and side-effects as compared to male hormone steroids

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Durch die Abspaltung von Adenosintriphosphat zur Adenosindiphosphat entwickelt sich y-Glutalmylcystein

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