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1 2 Assessment of the Risk of Hepatotoxicity with Kava Products

Simple in theory

Of importance, GLS inhibition and IDH1 mutations are synthetically lethal under oxidative stress, and GLS inhibition with CB-839 has been shown to selectively radiosensitize the IDH1 mutated xenograft GBM tumors [159]

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In addition, much progress has been made in preclinical studies focusing on environmental risk factors for SCZ and other neurodevelopmental disorders (NDD) that alter brain development such as psychosocial stress, maternal immune activation (MIA), and exposure to pollution (Bergdolt and Dunaevsky, 2019