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In 2009, the FDA imposed stronger language, requiring all over-the-counter acetaminophen products to warn that overdosing may cause "severe liver damage." The FDA's wording was nearly identical to what its expert panel had recommended 32 years earlier

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The few approved biomarker-based assays are only approved for use in emergency rooms to minimize the use of computed tomography scans, but [concerned about the assays sensitivity], a lot of clinicians are worried they will miss something. Consequently, despite FDA clearance of blood tests to diagnose concussions for Banyan Biomarkers in 2018, and BioMerieux and Abbott in 2024, demand is low