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Based on previous reports, APAP-induced cell death relies on the level of N-acetyl-p-benzoquinone imine (NAPQI) and its reaction with GSH or protein sulfhydryl groups [33]

induced psoriasis-like dermatitis using TLR7 agonist in the skin of mice, affecting intestinal immune cell and microbiota composition, which, in turn, led to an exacerbation of DSS-induced colitis (Kiyohara et al., 2018)

Showed a stronger expression level of cleaved Poly (ADP-ribose) polymerase (PARP) in these cell lines

PMID 3543057

Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis

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