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Description

The role of the microbiome in NAFLD and NASH (in Eng)

A dose-dependent decrease in body weight was shown, ranging from -1.3 kg in the placebo group to -1.4 kg in the 0.03 mg/kg leptin-treated group, and to -7.1 kg in the 0.30 mg/kg leptin-treated group (8)

This receptor modulation triggers a cascade of intracellular signaling events that ultimately result in the activation of hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids and glycerol