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doi: 10.1016/0167-5699(95)80067-0 159 WickG.KnoflachM.XuQ

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[27] Hypertrichosis (elongation, thickening, and enhancement of fine body hair), without evidence of virilism or endocrine abnormalities, is an embarrassing adverse effect that often occurs with oral minoxidil

Potential signs and symptoms include: Skin Raised, reddish patches covered with thick, silvery-white, shiny scales, which may be itchy Pinpoint bleeding spots appear when scales are scraped off (Auspitz sign) Systemic Fever, dehydration, and elevated white blood cell count may occur in severe cases Other Joint stiffness or pain, including inflammation or damage in psoriatic arthritis Diagnosis The diagnosis of psoriasis is based on a physical examination of the skin, scalp, and nails

Consequently, Vit B12 levels may decrease in PwPD due to heightened methylation requirements associated with LDopa therapy and alter myelin synthesis throughout carbohydrate and fat metabolism contributing to the development of NP (Uncini et al

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