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Abstract 4859: JNJ-64619178, a selective and pseudo-irreversible PRMT5 inhibitor with potent in vitro and in vivo activity, demonstrated in several lung cancer models

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FIGURE 1 2 Experimental sections 2.1 Synthesis Synthesis of CDs: 1.5 g of glutathione and 1.5 g of L-histidine were dissolved in 50 mL of formamide in a Teflon-lined autoclave