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Psychopharmacology 237 , 27392752 (2020)

Unlike other bacteria, Mtb has only one fumarase (Rv1098c), making it a vulnerable and attractive therapeutic target for drug development against Mtb [8, 223, 286]

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It gently cleanses the skin, removing excess oil, dirt, and impurities without stripping away natural moisture

This proposed hierarchical framework requires validation through systematic metabolomic and functional studies to establish the relative contributions of different metabolites, thereby informing targeted therapeutic strategies (Figure 1)