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You may fall asleep late, wake up too often, or wake up tired even after a full night in bed

In parallel, hepatocyte-directed PPAR gene therapy has been shown to enhance systemic -hydroxybutyrate availability, providing a neuroprotective energy substrate during cerebral metabolic crisis [128, 284, 285]

Further, having a healthy diet may seem to rule out any vitamin deficiency

Alterations in oocyte mitochondrial number and function are related to spindle defects and occur with maternal aging in mice and humans

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Mouse data, while foundational, should be integrated with complementary in vitro and in silico studies, as well as larger, more physiologically analogous animal models, to robustly predict clinical responses