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Critically, the success of this integrated model relies on patient stratification, which identifies individuals most likely to benefit from specific interventions while minimizing unnecessary treatments

Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

& Fujiwara, Y

Medications such as methadone to combat opioid addictions are regulated by cytochrome P450 genotypes (e.g., CYP2B6) and can also impact treatment response to addiction

10.1007/s10495-022-01714-3 54 ZhouM.YuY.LuoX.WangJ.LanX.LiuP.et al (2021)

Importantly, OS engages in profound bidirectional interactions with other pathogenic mechanisms