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LH, YS, and ZWi revised the manuscript

Notably, in a clinical trial of patients with severe acute pancreatitis, synbiotic prophylaxis containing Bifidobacterium , Lactobacillus , cornstarch, and maltodextrin was associated with a 2.5-fold increase in mortality and bowel ischemia compared to placebo (122)

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These applications often use lower maintenance doses (5-10 mg), making the 60 mg vial last even longer