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found that the MYC gene, which codes for the protein c-MYC, acted as an upstream gene

doi: 10.1002/1531-8249(199907)46:1 3.0.co;2-y

GPX4 promotes proliferation and ferroptosis resistance in lung cancer, while GPX4 inhibitor RSL3 limits proliferation, migration, and invasion of cisplatin-resistant A549 cells (Ni J

Targeted disruption of the JAK2/STAT3 pathway in combination with systemic administration of paclitaxel inhibits the priming of ovarian cancer stem cells leading to a reduced tumor burden