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Description

ISBN 978-0-8147-7082-5

Clin Pharmacol Drug Dev 2020;9(3):395410

The transcription factor NrF2 stands as an opponent for SLC711-p53-mediated repression since it promotes the expression of SLC7A11 as one of its target genes, which opposes ferroptosis [344]

SAM-competitive PRMT5 inhibitor PF-06939999 demonstrates antitumor activity in splicing dysregulated NSCLC with decreased liability of drug resistance discovery of SAM-competitive PRMT5 inhibitor PF-06939999