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176 NieslerB.KuertenS.DemirI

This peroxidase uses the antioxidant tripeptide glutathione (GSH) instead of thioredoxin as the physiological reductant to reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or to hydrolyze the sn-2 ester (alkyl) bond of phospholipids (phospholipase A(2) [PLA(2)] activity)

Mikelsaar, M

Progress in the understanding of the pathophysiology of APAP hepatotoxicity revealed that the key oxidant in mitochondria is peroxynitrite, a reaction product of superoxide and nitric oxide [71]

Direct and indirect costs of rheumatoid arthritis to an employer

Furthermore, NOX2 activity was downregulated in peripheral neutrophils of ALS patients, which also correlated with improved survival and disease outcomes (Marrali et al., 2014)