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This may justify the fact that these hormones are involved in the control of the synthesis and secretion of GH, a hormone with important metabolic actions: hyperglycemic, lipolytic, and anabolic, which is stimulated by ghrelin and inhibited by nesfatins

European Journal Pharmacology, 678 (13), 3238

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(2007) demonstrated that exposing human astrocytes to the HIV-1 envelope glycoprotein gp120 led to significant neurotoxic consequences, including diminished cell viability, increased apoptosis, lipid peroxidation, and, reduced expression of GS [125]