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Consequently, it is characterized by a notable reduction in beneficial butyrate-producing bacteria (which weakens intestinal barrier function) and an increase in pathogenic Gram-negative bacteria (which promote systemic inflammation)

Therefore, various APAP doses were tested to assess susceptibility to APAP-induced toxicity, aiming to investigate potential differences in tolerance between wild-type and hepsin / mice

doi: 10.3390/antiox9090901

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