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Further investigation into the testicular microenvironment using a co-culture system of senescent TM3 Leydig cells and GC-1 spg spermatogonia revealed that H2O2-induced senescent TM3 cells secreted increased levels of SASP factors, particularly IL-6 and TGF-

Faculty of Pharmaceutical Sciences, Toho University, Chiba 274-8510, Japan

doi:10.1080/1061186x.2023.2290453 91

Whether its the vitamins you take or the foods you eat, many things you used to consume before pregnancy may not be suitable for nine months

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CONCLUSION Based on the comprehensive review presented, EV-based therapeutics demonstrate transformative potential within AD research