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In a similar study, blood ERGO levels were lower in individuals with Parkinson's Disease (PD) than with age-matched individuals without the disease (Reference Hatano, Saiki and Okuzumi12)

Exact numbers vary by trial design, dose, and patient population, so clinics should reference the FDA label and pivotal trial publications directly for precise figures

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Together, these results provide mechanistic insight into how IGF-1 maintains adult bone mass, while also providing a further rationale for its therapeutic targeting to treat age-related osteoporosis