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Post-surgical / structural changes: For folks with gender-affirming surgeries, anatomy, nerve changes, and implant types may affect function

It emerges that these senescent cells can be eradicated in mice using a drug that interferes with the activity of the protein FOXO4

Melnyk S, Pogribna M, Pogribny IP, Yi P, and James SJ (2000)

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Participants All patients had extensive workups by their private physicians at the time of the onset of their symptoms

The gut microbiome influences systemic immune function, and disruptions to gut health can exacerbate autoimmune conditions