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Traditionally, farmed animals would have got their B12 from water and eating food from the ground but with so many now confined in factory farms, animals themselves are given B12 supplements

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Prolonged overdose of B6 (150-200 mg/day) over weeks can cause severe sensory-nervous-system dysfunction and ataxia.37 With normal usage serious adverse effects are not reported for pyridoxine (vitamin B6), however, diarrhoea, emesis and rosacea-like dermatitis may be observed in some cases (38)