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His experience is consistent with what the mechanistic literature would predict

Invest in larger-capacity equipment, such as industrial-scale peptide synthesizers and preparative HPLC systems

Not always - but it's worth evaluating early, especially if there's a known reason to suspect low iron stores

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Example: One patient from Arizona came to us because, despite being maximized on treatment for Rheumatoid arthritis with DMARDs and a biologic, her disease control was very poor