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Biochim Biophys Acta (BBA) - Bioenergetics

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The goal was to create a compound that mimicked hGHs ability to regulate fat metabolism but without impacting insulin sensitivity or promoting the kind of cellular proliferation associated with IGF-1

Additional assays commonly measure fatty acid oxidation rates, intracellular lipid accumulation, and downstream signaling intermediates such as cyclic AMP and protein kinase A activation