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10.1111/j.1365-2990.2010.01135.x [DOI] [PMC free article] [PubMed] [Google Scholar] Gabrielli M., Bonazzi P., Scarpellini E., Bendia E., Lauritano E

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Studies show that silymarin can be effective at doses of 200-600mg per day for most users.2 Silymarin is lipophilic and hydrophobic, meaning that it has an affinity for fats and is largely insoluble in water

Al Asmari AK, Al Sadoon KT, Obaid AA, Yesunayagam D, Tariq M (2017) Protective effect of quinacrine against glycerol-induced acute kidney injury in rats