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Nevertheless, dose-based models require large amounts of data which might be expensive or difficult to get 45

Mechanistic evidence relies heavily on animal studies (e.g., mouse neurotransmitter experiments) with insufficient large-scale human randomized controlled trials (RCTs) to confirm causality

Systemic Allergic Reactions (Anaphylaxis) Her are some warning signs requiring immediate emergency services: Generalized urticaria (hives) or widespread itching beyond injection site Swelling of lips, face, tongue, or throat Shortness of breath, wheeze, chest tightness, difficulty breathing Dizziness, lightheadedness, syncope Rapid heart rate with pallor, collapse, or hypotension Call 911 immediately, as anaphylaxis requires epinephrine and emergency care

Singh S, Kumar A (2019) Protective Effect of Edaravone on Cyclophosphamide Induced Oxidative Stress and Neurotoxicity in Rats

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