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The molecular link between mitochondrial oxidative stress/DNA damage and ferroptosis in LN (223) is also poorly defined: it is unknown whether mitochondrial dysfunction directly triggers iron overload/lipid peroxidation or indirectly by suppressing antioxidant networks (e.g., Nrf2/GPX4)

L-Carnitine This naturally occurring amino acid plays a vital role in the metabolism of fat

Differentiation of monocytes into macrophages induces the upregulation of histamine H1 receptor

While direct studies in AP are limited, these findings suggest melatonins potential in modulating mitochondrial quality control in pancreatic inflammation

There was no consistent pattern of acquisition method used across studies

Details are provided in the Table 1