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doi: 10.1073/pnas.1913904117 78 Man AnhH.LinhD

possibly increases the secretion of prostaglandin E2 (PGE 2 ) (288), somatostatin (289), and neuropeptide substance P (290) enhancing infection symptoms and promote granuloma formation

Without thorough correlative assessments of tissue-level biomarkers (such as Ki-67, 8-OHdG, and NF-B) or genetic stratification (such as GSTM1 status for SFN efficacy), many trials only used PSA kinetics

Tissue Specificity: While both peptides promote healing across multiple tissue types, they show some differences in tissue specificity