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While in vitro equilibrations between redox couples such as roGFP2 and GSH/GSSG require minutes or even hours to reach a thermodynamic endpoint (G = 0), enzyme-catalyzed thiol-disulfide exchange reactions usually occur very rapidly and either maintain or reach a steady state (G 0) 7,31,32,60,63,67,78,79

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Our bodies are constantly producing free radicals (uncharged, highly reactive molecules with unpaired electrons)

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[DOI] [PubMed] [Google Scholar] 133.van Gool J.D., Hirche H., Lax H., De Schaepdrijver L