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This evidence lends support to the fact that mosaic antigens and/or sequential boosting of antibodies may be needed to selectively expand cross-reactive immunity

Most people tolerate glutathione well, but mild digestive symptoms or headaches can occur in some individuals, particularly at higher doses

Although a more recent ICOP 2020 taxonomy existsand a recent systematic review found no material clinical or epidemiologic differences versus ICHD-IIIwe based enrollment on ICHD-III to preserve continuity and comparability 23,24

De Leo E, Elmonem MA, Berlingerio SP, Berquez M, Festa BP, Raso R, Bellomo F, Starborg T, Janssen MJ, Abbaszadeh Z, Cairoli S, Goffredo BM, Masereeuw R, Devuyst O, Lowe M, Levtchenko E, Luciani A, Emma F, Rega LR (2020) Cell-based phenotypic drug screening identifies luteolin as candidate therapeutic for nephropathic cystinosis

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