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& Pouyssegur, J

Antioxidant defense system During oxidative stress and other stress conditions increased levels of H 2 O 2 is associated with elevated production of antioxidant enzymes 31

doi: 10.1073/pnas.2513640122 Mondal, Victor, Ross-Munro, Emily, Firipis, Kate, Balasuriya, Gayathri K., Kumari, Ritu, Hossen, Md

& Palese, P

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However, given the proper circumstances and enough time, a protein that has unfolded under sufficiently gentle conditions can refold and may again exhibit biological activity (Figure 2.5.1)