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Description

Lipid metabolism is closely linked to ferroptosis, as it involves the generation and accumulation of lipid peroxides

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doi: 10.1126/science.1188302 123 KimHJHuhDHamiltonGIngberDE

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Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy

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Thus, in this experiment, we used the structurally distinct HDM2 inhibitor MI-773, which like nutlin-3 potently suppressed ferroptosis (Fig 1C)

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