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In this study, the degrees of vascular activity and the extent of damage were expressed using BVAS and VDI, respectively

Some studies have suggested that abnormalities in the function of these neurotransmitters may be involved in the development of FM 20,21

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There could also be residual confounding by the lingering effects of anti-diabetic medications such as metformin [30]

EPAC2 protein not only serves as a key intracellular effector of cAMP but also acts as an upstream activator of the small GTPase RAP1, as supported by our RNA sequencing data (Fig

High blood pressure and diabetes can be contributing factors