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VEGF binding induces the dimerization of VEGFR-2 molecules, leading to the activation of intrinsic kinase activity within the intracellular domain, which in turn leads to autophosphorylation of specific tyrosine residues on the receptor

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[DOI] [PubMed] [Google Scholar] 53.NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice