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126 Proof of concept for the hypothesis that hypoactivation of the mTOR-P70S6K pathway leads to inhibition of OPC proliferation and maturation, and subsequently hypomyelination is provided by the fact that conditional mTOR knockout in mouse OPCs leads to various myelination defects

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doi: 10.3390/ijms22168677

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GPX3 and MYC may influence the RA immune microenvironment by regulating macrophage polarization, T cell function, and NK cell activation