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Theyre real, Bricker said

It plays a significant role in promoting moderate mitochondrial stress, which activates Nrf2, adenosine 5-monophosphate-activated protein kinase (AMPK), and SIRT1 and SIRT3, all of which are involved in anti-inflammatory and antioxidant responses (188)

their Table 17.9 does list (their entry 40) the related compound pyridine , 3-(1-methyl-2pyrrolin-2-yl)-6-methyl- (aka 6-methy-2,3-dehydronicotine) as having been reported in internal tobacco industry documents 8,9 as present in a Turkish tobacco essential oil