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Supporting the view that APAP is neurotoxic, a 2010 study of adult rats demonstrated that APAP induces the death of cortical neurons at concentrations lower than those required to induce acute liver failure [13].A recent summary statement by Bauer et al

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13 C-NMR (100 MHz, CDCl 3 ) ppm = 169.0, 159.1, 149.7, 143.2, 133.3, 124.1, 123.2, 119.5, 118.5, 113.6, 111.1, 109.7, 49.9, 46.4, 26.5, 24.5

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Our laboratory has also explored this approach using the Girard T (GT) derivative, which has been previously used to analyze keto steroids Citation[39,40]