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In contrast, in radioresistant SW837 cells, no significant alterations in cell cycle distribution were observed at 48 h post treatment in SW837 cells ( Figure 2B )

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We have identified that contrarily to other COX2-derived pro-inflammatory enzymes Lipocalin-Type Prostaglandin D Synthase (L-PGDS, the enzyme encoded by Ptgds ) increases during differentiation, together with the rise in PGD 2 levels

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The metabolite-receptor interaction system formed by the co-evolution of microorganisms and their hosts builds a multi-organ defense system by precisely regulating epithelial integrity, neurovascular function, and energy metabolism balance ( 3.1 The AHR-IL-22 axis This section elaborates on a key downstream axis of the AHR signaling pathway, introduced in the overview, which is central to maintaining intestinal homeostasis