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Evolving Therapeutics in Multiple Myeloma Highly effective treatments are available in early-line settings of multiple myeloma management, such as proteasome inhibitors, immunomodulatory drugs (IMiDs), corticosteroids, and multiple drug combinations, including anti-CD38 antibodies, but treatment options for progressive disease following initial lines of therapy have historically been limited

10.1016/j.ceb.2014.09.010 264 RicordiC.Garcia-ContrerasM.FarnettiS

the anti-cancer compound is selected from the group consisting of abraxane, doxorubicin, pamidronate disodium, anastrozole, exemestane, cyclophosphamide, epirubicin, toremifene, letrozole, trastuzumab, megestroltamoxifen, paclitaxel, docetaxel, capecitabine, goserelin acetate, zoledronic acid, vinblastine, etc.),, an antisense molecule, an SiRNA, and the like

2.12 Statistical analysis The data was analyzed using the SPSS software system (version 22)

In a randomized, double-blind, placebo-controlled Phase II trial involving 204 patients with mild to moderate plaque psoriasis, daily oral administration of Serlopitanta selective NK1R antagonistled to a statistically significant yet modest reduction in psoriasis-associated pruritus, indicating that NK1R blockade alone may not fully account for the complex mechanisms of itch and that other mediators are likely to play major roles [75]

VIROLOGY 40 (01), 5157