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2012;33:e100318

GSH-independence can be conferred by mutations at the protomer interface, consistent with GSH binding to protomers driving the formation of pentameric units critical to assembly 16,17

Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models

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In scientific literature, NNMT is recognized as an enzyme that methylates nicotinamide (a precursor of NAD+) using S-adenosylmethionine (SAM) as the methyl donor, converting it to 1-methylnicotinamide (MNA) and potentially affecting cellular NAD+ availability