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While IGF-1 has important physiological functions, elevated levels carry potential concerns including increased cell proliferation that may support tumor growth in individuals with cancer or pre-cancerous conditions, accelerated aging processes through growth pathway activation, potential cardiovascular effects with chronic elevation, and metabolic consequences including effects on glucose and lipid metabolism

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This is an artist's depiction of the Juno spacecraft, which is currently orbiting Jupiter

Effect of IBD medications on COVID-19 outcomes: results from an international registry