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A small trial in methotrexate (MTX)-resistant RA suggested that everolimus plus MTX could alleviate joint symptoms, though larger confirmatory studies are needed (244)

Similar content being viewed by others Introduction In the tumor microenvironment (TME), malignant cells and stromal cells produce various angiogenic factors to induce neovascularization, vascular remodeling, tumor growth, and metastasis 1