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4 integrates extracellular stress and growth cues to regulate cell-cycle progression, apoptosis, and differentiation, and frequently cooperates with NF-B signaling to promote cancer cell survival and metastasis

Conversely, pharmacological antioxidants are synthetically created to enhance their antioxidant effects through improved stability, increased bioavailability, and enhanced cellular targeting

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Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients An emollient that softens the skin and forms a protective layer on its surface

Shiels, 2020)