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Thus, the data from this study support the notion that BH4 can improve oxidative damage and methylation abnormalities in children with ASD with a large effect size, with the caveat that this effect may be more pronounced in those with the more severe abnormalities at baseline

Details of the CpG island size, location, and CpG content are described in the supplementary methods (Supplementary Table S3)

Creatine Creatine plays a central role in all high energy demanding systems such as the CNS and muscular system under intensive sport training

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