Then, independent of allowing you neurons to get this easier source of energy...if the neurons are using glucose because they need energy but the glucose can't be used to repair that damage to the pentose phosphate pathway, I think that's one component of it in terms of the temporal effects, like how soon after the damage
Specifically, recent studies in a model of ischemia/reperfusion injury in mice demonstrated that GRP78 activity was suppressed by the overexpression of p62, a macroautophagy driver (Quan et al., 2025)
F.ZhengW.DuanY.et al
Cochrane database of systematic reviews , (2010)
Giving Your Health Your Best Shot: Vitamin B12 Injections Can Boost Your Energy I feel tired and weak. I have no energy to get things done. I feel off-balance. I cant think clearly. I get feelings of pins and needles in my hands and feet. My heart feels like its racing. If these complaints sound familiar, they may be signs that your body is deficient in vitamin B12
low-molecular weight crosslinking reagents may be used, especially when hydrophilic high-molecular weight backbone moieties are used for the formation of biodegradable hydrogels according to the invention