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& de la Guardia, M

*Correspondence: Lei Zang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

CoA = coenzyme A

Silflow et al., 2001

The interaction and mutual promotion of these three factors are thought to be responsible for the concentrated epidemic of cretinism in Central Africa ( Figure 2 It is thought-provoking that Se supplementation in iodine-deficient populations in this region can have serious and incalculable consequences ( This enlightens us that Se supplementation should not be done indiscriminately in patients with congenital hypothyroidism (CH)

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